Obtaining of small-dispersed microspheres using the method of mechanical and plasma separations
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Keywords:
microsphere, separation, dispersion, plasma, embolizationAbstract
In this paper the method of obtaining of small-dispersed microspheres based on a mechanical and plasma separations is considered. This method allows for obtaining microparticles with high dispersion produced from any materials. The advantages of this technology compared to other analogues are its simplicity and low energy consumption. In addition, this method can be used as a tool which can control the lower and upper limit in particle size distribution in powder. This procedure could be a promising application for obtaining of emboli in cancer treatment.
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3 Eunmi Leeand, Bumsang Kim, Smart deliverysystem for cosmeticing redients using pH-sensitive polymer hydrogel par-ticles // Korean J. Chem. Eng. – 2011. – No.28(6). –P.1347-1350.
4 Tamás Szabó, Lívia Molnár-Nagy, János Bognár, Lajos Nyikos, Judit Telegdi, Self-healing microcapsules and slowrelease microspheresinpaints // Progressin Organic Coatings. – 2011. – Vol. 72. – P. 52–57.
5 Humble R.A., Elsinga G.E., Scarano F., and B.W. Van Oudheusden, Three-dimension alinstantaneous structure of a shock wave / turbulent boundary layer interaction // Journal of Fluid Mechanics. – 2009. – Vol. 622. – P.33-62.
6 Sigaev V.N., Atroschenko G.N., Savinkov V.I., Sarkisov P.D., Babajew G., Lingel K., Lorenzi R., Paleari A. Structural rear¬rangement at theyttrium-depleted surface of HCl-processed yttrium alumino-silicate glass for 90Y-microsphere brachy therapy // Mater. Chem. Phys. – 2012. – Vol. 133. – P.24-28.
7 Trewyn B.G., Nieweg J.A., Zhao Y., Lin V.S.-Y. // Chem. Eng. J. – 2008. – Vol.137. – P.23.
8 Vivero-Escoto J.L., Slowing I.I., Trewyn B.G., Lin V.S.-Y. // Small. – 2010. – Vol.6. – P.1952.
9 Antonio B., Gianpaolo C., Anna M.I., Elias B. Quality-Improvement Guidelines for hepatic transarterial сhemoembolization // Cardiovascintervent Radiol. May 2012. Cardio vascular and interventional radio-logical society of Europe (CIRSE), 2012.
10 Bastian P., Bartkowski R., Köhler H. etal. Chemoembolization of experimental liver metastases. Part I: distribution of biode¬gradable microspheres of different sizes in an animal model for the locoregion-altherapy // Eur. J. Pharm. Biopharm. – 1998. – №46. – Р. 243-254.
11 Bilbao J.I., de Luis E., Garcíade Jalón J.A. etal. Comparative study of four different spherical embolic particles in an animal model: a morphologic and his tologice valuation // J. Vasc. Interv. Radiol. – 2008. – № 19. – Р. 1625-1638.
12 Bonomo G., Pedicini V., Monfardini L. etal. Bland embolization in patients with unresectable hepatocelllular carcino maus¬ing precise, tightly sized calibrated antiinflammatory microparticles: first clinical experience and 1 year follow up // Cardio- vasc. Intervent. Radiol. – 2010. – № 33. – Р. 522–529.
13 Cruz J.E., Saksena R., Jabbour S.K. etal. The power of genes: a case of unusually severe system ictoxicity afte rlocalized hepatic chemoembolization with irinotecan-eluted microspheres for metastatic colon cancer // Ann. Pharmacother. – 2014. – Dec, №48 (12).
14 Dinca H., Pelage J.P., Baylatry M.T. etal. Why do small sized oxo-rubicin-eluting microspheres induce more tissue necrosis than larger ones? A comparative study in healthy pig liver (oral communication 2206-2) // CIRSE Annual. Meeting. Lisbon, 2012.
15 Gadaleta C.D. Trans arterial chemoembolization as a therapy for liver tumors: New clinical developments and suggestions for combination with angiogenesis inhibitors Gadaleta C.D., Ranieri G. // Crit. Rev. Oncol. Hematol. – 2011. – № 80 (1). – Р. 40-53.
16 Gonzalez M.V., Tang Y., Phillips G.J. et al. Doxorubicineluting beads-2: methods for evaluating drug elution and in-vitro: in-vivo correlation // J. Mater. Sci. Mater. Med. – 2008. – № 19. – Р. 767-775.
17 Grosso M., Vignali C., Quaretti P. Et al. Trans arterial chemoembolization for hepatocellular carcinoma with drug-eluting microspheres: preliminary results from an Italian multicentre study // Cardiovasc Intervent. Radiol. – 2008. – № 31. – Р. 1141-1149.
18 Batryshev D.G., Ramazanov T.S., Dosbolayev M.K., Gabdullin M.T. A Method of Separation of Polydisperse Particles in the Plasma of Radio-Frequency Discharge // Contrib. Plasma Phys. – 2015. – V. 55, №. 5. – P. 407–412.
19 Батрышев Д.Г., Рамазанов Т.С., Досболаев М.К., Габдуллин М.Т., Оразбаев С.А. Сепарация полидисперсных пылевых частиц в плазме высокочастотного емкостного разряда // Журнал Известия НАН РК, Серия физико-математическая. – 2014. – Вып. 2. – С.145–148.
20 Batryshev D.G., Ramazanov T.S., Dosbolayev M.K., Gabdullin M.T. Separation Process of Polydisperse Particles in the Plasma of Radio-Frequency Discharge // Journal of nano- and electronic physics. – 2014. – V.6, №.3. – P. 30–32.
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Бaтрышев Д., Рамазанов, Т., Досболаев, М., Габдуллин, М., & Ерланулы, Е. (2016). Obtaining of small-dispersed microspheres using the method of mechanical and plasma separations. Recent Contributions to Physics (Rec.Contr.Phys.), 59(4), 32–37. Retrieved from https://bph.kaznu.kz/index.php/zhuzhu/article/view/489
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Plasma Physics
